British Society of Cutaneous Allergy (BCSA)

Caine Mix

What are the aims of this patient information leaflet?

This leaflet has been written to help you understand more about your contact allergy. It tells you what a contact allergy is, what causes this allergy and what you can do about it.

What is contact allergy?

Dermatitis, also known as eczema, describes a type of inflammation of the skin. Contact dermatitis or contact eczema is a term used when this inflammation is caused by direct or indirect skin contact with something in your environment. Allergic contact dermatitis occurs when your immune system causes allergy to a very specific chemical or substance that has been in contact with the skin.

What causes your specific allergy?

Your patch tests indicate that you have a contact allergy to caine mix.

What is caine mix?

Caine mix is a local anaesthetic made up of benzocaine, dibucaine hydrochloride, and tetracaine hydrochloride. It is found in products that reduce pain, itching, and stinging.

What are some products that contain caine mix?


  • Anthisan plus
  • BurnEz
  • Wasp-eze spray
  • Lanacaine
  • Solarcaine
  • Rinstead gel
  • AAA Sore throat spray
  • Dequacaine
  • Merocaine lozenges
  • Tyrozets
  • Vicks Ultra
  • Chloraseptic
  • Intralgin.

Cinchocaine (Dibucaine)

  • Nupercainal
  • Proctosedyl
  • Scheriproct
  • Ultraproct
  • Uniroid-HC.

Amethocaine (Tetracaine)

  • Anethaine
  • Ametop gel
  • Eludril spray
  • Tetracaine eye drops.

You are very unlikely to have any problems with injectable anaesthetics such as those used by your dentist or for skin surgery.

Remember, always check the label, these lists can never be complete and ingredients change.

How can I manage my allergy?

This means that you should avoid putting products containing caine mix onto your skin in the future.

Self-care (what can I do?)

Always check the ingredient listing on the product, package or package insert as these lists can never be complete and ingredients change. This is particularly important for any products purchased outside the EU where some allergens may not be banned.

Created: 2016